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Document type:
journal article 
Author(s):
Büning, C; Schmidt, HH; Molnár, T; Drenth, JP; Fiedler, T; Gentz, E; Todorov, T; Baumgart, DC; Sturm, A; Nagy, F; Lonovics, J; de Jong, DJ; Landt, O; Kage, A; Nickel, R; Büttner, J; Lochs, H; Witt, H 
Title:
No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts. 
Abstract:
BACKGROUND: A recent study reported that the c.30T>A (p.Cys10Ter; rs2043211) variant, in the CARD8 (TUCAN) gene, is associated with Crohn's disease (CD). The aim of this study was to analyze the frequency of p.C10X in 3 independent European (IBD) cohorts from Germany, Hungary, and the Netherlands. METHODS: We included a European IBD cohort of 921 patients and compared the p.C10X genotype frequency to 832 healthy controls. The 3 study populations analyzed were: (1) Germany [CD, n = 317; ulcerat...    »
 
Journal title abbreviation:
Inflamm Bowel Dis 
Year:
2008 
Journal volume:
14 
Journal issue:
Pages contribution:
332-7 
Language:
eng 
Print-ISSN:
1078-0998 
TUM Institution:
hrungsmedizin