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Dokumenttyp:
journal article 
Autor(en):
Lämmermann, T; Bader, BL; Monkley, SJ; Worbs, T; Wedlich-Söldner, R; Hirsch, K; Keller, M; Förster, R; Critchley, DR; Fässler, R; Sixt, M 
Titel:
Rapid leukocyte migration by integrin-independent flowing and squeezing. 
Abstract:
All metazoan cells carry transmembrane receptors of the integrin family, which couple the contractile force of the actomyosin cytoskeleton to the extracellular environment. In agreement with this principle, rapidly migrating leukocytes use integrin-mediated adhesion when moving over two-dimensional surfaces. As migration on two-dimensional substrates naturally overemphasizes the role of adhesion, the contribution of integrins during three-dimensional movement of leukocytes within tissues has rem...    »
 
Zeitschriftentitel:
Nature 
Jahr:
2008 
Band / Volume:
453 
Heft / Issue:
7191 
Seitenangaben Beitrag:
51-5 
Sprache:
eng 
Print-ISSN:
0028-0836 
TUM Einrichtung:
hrungsmedizin