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Document type:
journal article 
Author(s):
Lieb, W; Zeller, T; Mangino, M; Götz, A; Braund, P; Wenzel, JJ; Horn, C; Proust, C; Linsel-Nitschke, P; Amouyel, P; Bruse, P; Arveiler, D; König, IR; Ferrières, J; Ziegler, A; Balmforth, AJ; Evans, A; Ducimetière, P; Cambien, F; Hengstenberg, C; Stark, K; Hall, AS; Schunkert, H; Blankenberg, S; Samani, NJ; Erdmann, J; Tiret, L 
Title:
Lack of association of genetic variants in the LRP8 gene with familial and sporadic myocardial infarction. 
Abstract:
Coronary artery disease (CAD) and myocardial infarction (MI) have a genetic basis, but the precise genetic underpinning remains controversial. Recently, an association of the LRP8 R952Q polymorphism (rs5174) with familial premature CAD/MI was reported. We analysed rs5174 (or the perfect proxy rs5177) in 1,210 patients with familial MI and 1,015 controls from the German MI Family study, in 1,926 familial CAD (1,377 with MI) patients and 2,938 controls from the Wellcome Trust Case Control Consorti...    »
 
Journal title abbreviation:
J Mol Med 
Year:
2008 
Journal volume:
86 
Journal issue:
10 
Pages contribution:
1163-70 
Language:
eng 
Print-ISSN:
0946-2716 
TUM Institution:
hrungsmedizin