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Document type:
journal article 
Author(s):
Uberla, K; Rosenwirth, B; Ten Haaft, P; Heeney, J; Sutter, G; Erfle, V 
Title:
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV-infected rhesus monkeys undergoing antiretroviral therapy. 
Abstract:
BACKGROUND: The long-term benefits of highly active antiretroviral therapy in HIV-infected patients are limited by emergence of drug-resistant variants and side effects. Therefore, we studied the concept of therapeutic immunization in 18 rhesus monkeys infected with a highly pathogenic simian immunodeficiency virus (SIV) swarm. METHODS: Monkeys were treated with the reverse transcriptase inhibitor (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) for 19 weeks starting 10 days after infection. Afte...    »
 
Journal title abbreviation:
J Med Primatol 
Year:
2007 
Journal volume:
36 
Journal issue:
Pages contribution:
2-9 
Language:
eng 
Print-ISSN:
0047-2565 
TUM Institution:
r Virologie