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- Dokumenttyp:
- Journal Article; Article
- Autor(en):
- Riemenschneider, M; Schoepfer-Wendels, A; Friedrich, P; Konta, L; Laws, SM; Mueller, JC; Kurz, A; Förstl, H
- Titel:
- No association of vacuolar protein sorting 26 polymorphisms with Alzheimer's disease.
- Abstract:
- Using a case-control sample we evaluated a possible involvement of the Vacuolar protein sorting 26 (VPS26) gene in the pathogenesis of AD. VPS26 located at 10q22.1 denotes a retromer subunit functionally involved in the cellular trafficking of Memapsin 2 (BACE). Genotyping of eight single nucleotide polymorphisms covering the complete VPS26 gene and haplotypic analysis revealed no association with AD. Thus, we conclude that VPS26 can be excluded as a major positional and functional candidate gen... »
- Zeitschriftentitel:
- Neurobiol Aging
- Jahr:
- 2007
- Band / Volume:
- 28
- Heft / Issue:
- 6
- Seitenangaben Beitrag:
- 883-4
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.neurobiolaging.2006.05.009
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/16784798
- Print-ISSN:
- 0197-4580
- TUM Einrichtung:
- Klinik und Poliklinik für Psychiatrie und Psychotherapie
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