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Dokumenttyp:
journal article 
Autor(en):
Riemenschneider, M; Schoepfer-Wendels, A; Friedrich, P; Konta, L; Laws, SM; Mueller, JC; Kurz, A; Förstl, H 
Titel:
No association of vacuolar protein sorting 26 polymorphisms with Alzheimer's disease. 
Abstract:
Using a case-control sample we evaluated a possible involvement of the Vacuolar protein sorting 26 (VPS26) gene in the pathogenesis of AD. VPS26 located at 10q22.1 denotes a retromer subunit functionally involved in the cellular trafficking of Memapsin 2 (BACE). Genotyping of eight single nucleotide polymorphisms covering the complete VPS26 gene and haplotypic analysis revealed no association with AD. Thus, we conclude that VPS26 can be excluded as a major positional and functional candidate gen...    »
 
Zeitschriftentitel:
Neurobiol Aging 
Jahr:
2007 
Band / Volume:
28 
Heft / Issue:
Seitenangaben Beitrag:
883-4 
Sprache:
eng 
Print-ISSN:
0197-4580 
TUM Einrichtung:
r Psychiatrie und Psychotherapie