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Dokumenttyp:
journal article 
Autor(en):
Döring, B; Pfitzer, G; Adam, B; Liebregts, T; Eckardt, D; Holtmann, G; Hofmann, F; Feil, S; Feil, R; Willecke, K 
Titel:
Ablation of connexin43 in smooth muscle cells of the mouse intestine: functional insights into physiology and morphology. 
Abstract:
Connexin43 (Cx43) gap-junction channels are highly abundant in intestinal smooth muscle but their functional impact has not been studied so far. Here, we have aimed to elucidate the functional role of Cx43 in the tunica muscularis of the mouse intestine in vivo. Transgenic mice with conditional deletion of Cx43 in smooth muscle cells (SMC) were generated. Histological investigations by immunofluorescence analyses and organ-bath recordings to assess the contractility of intestinal tissue strips w...    »
 
Zeitschriftentitel:
Cell Tissue Res 
Jahr:
2007 
Band / Volume:
327 
Heft / Issue:
Seitenangaben Beitrag:
333-42 
Sprache:
eng 
Print-ISSN:
0302-766X 
TUM Einrichtung:
r Pharmakologie und Toxikologie