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Dokumenttyp:
journal article 
Autor(en):
Bader, FG; Lordick, F; Fink, U; Becker, K; Hofler, H; Busch, R; Siewert, JR; Ott, K 
Titel:
Paclitaxel in the neoadjuvant treatment for adeno carcinoma of the distal esophagus (AEG I). A comparison of two phase II trials with long-term follow-up. 
Abstract:
INTRODUCTION: We report a comparative analysis of 2 sequential, prospective phase II trials on the efficacy of platinum/leucovorin/5-fluorouracil (PLF) +/- paclitaxel (T-PLF) in the neoadjuvant treatment of adenocarcinoma of the esophagus (AEG I). PATIENTS AND METHODS: Inclusion criteria were histologically proven, locally advanced AEG I stage uT3/4 anyN cM0/M1a. 67 patients were treated with either PLF (n = 32) or T-PLF (n = 35). Paclitaxel (80 mg/m(2)) was added to PLF on days 1, 15, and 29. P...    »
 
Zeitschriftentitel:
Onkologie 
Jahr:
2008 
Band / Volume:
31 
Heft / Issue:
Seitenangaben Beitrag:
366-72 
Sprache:
eng 
Print-ISSN:
0378-584X 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik; Chirurgiesche Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie; r Medizinische Statistik und Epidemiologie