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Document type:
journal article 
Author(s):
Bink, K; Haralambieva, E; Kremer, M; Ott, G; Beham-Schmid, C; de Leval, L; Peh, SC; Laeng, HR; Jütting, U; Hutzler, P; Quintanilla-Martinez, L; Fend, F 
Title:
Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics. 
Abstract:
Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma. Since cytogenetic data on extramedullary plasmacytoma are lacking, we studied 38 cases of this type of neoplasm by fluorescence in situ hybridization. Fourteen cases (37%) contained IGH breaks, including six with a t(4; 14) translocation. No translocations t(11; 14), t(14; 16), t(8; 14), nor breaks involving MALT1, BCL6 or FOXP1 were found. Loss of 13q (40%), as well as chromosomal gains (...    »
 
Journal title abbreviation:
Haematologica 
Year:
2008 
Journal volume:
93 
Journal issue:
Pages contribution:
623-6 
Language:
eng 
Print-ISSN:
0390-6078 
TUM Institution:
r Allgemeine Pathologie und pathologische Anatomie