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Dokumenttyp:
journal article 
Autor(en):
Bink, K; Haralambieva, E; Kremer, M; Ott, G; Beham-Schmid, C; de Leval, L; Peh, SC; Laeng, HR; Jütting, U; Hutzler, P; Quintanilla-Martinez, L; Fend, F 
Titel:
Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics. 
Abstract:
Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma. Since cytogenetic data on extramedullary plasmacytoma are lacking, we studied 38 cases of this type of neoplasm by fluorescence in situ hybridization. Fourteen cases (37%) contained IGH breaks, including six with a t(4; 14) translocation. No translocations t(11; 14), t(14; 16), t(8; 14), nor breaks involving MALT1, BCL6 or FOXP1 were found. Loss of 13q (40%), as well as chromosomal gains (...    »
 
Zeitschriftentitel:
Haematologica 
Jahr:
2008 
Band / Volume:
93 
Heft / Issue:
Seitenangaben Beitrag:
623-6 
Sprache:
eng 
Print-ISSN:
0390-6078 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie