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Dokumenttyp:
journal article 
Autor(en):
Donath, MY; Schumann, DM; Faulenbach, M; Ellingsgaard, H; Perren, A; Ehses, JA 
Titel:
Islet inflammation in type 2 diabetes: from metabolic stress to therapy. 
Abstract:
Decreases in both mass and secretory function of insulin-producing beta-cells contribute to the pathophysiology of type 2 diabetes. The histology of islets from patients with type 2 diabetes displays an inflammatory process characterized by the presence of cytokines, apoptotic cells, immune cell infiltration, amyloid deposits, and eventually fibrosis. This inflammatory process is probably the combined consequence of dyslipidemia, hyperglycemia, and increased circulating adipokines. Therefore, mo...    »
 
Zeitschriftentitel:
Diabetes Care 
Jahr:
2008 
Band / Volume:
31 Suppl 2 
Seitenangaben Beitrag:
S161-4 
Sprache:
eng 
Print-ISSN:
0149-5992 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie