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Dokumenttyp:
journal article 
Autor(en):
Beer, AJ; Niemeyer, M; Carlsen, J; Sarbia, M; Nährig, J; Watzlowik, P; Wester, HJ; Harbeck, N; Schwaiger, M 
Titel:
Patterns of alphavbeta3 expression in primary and metastatic human breast cancer as shown by 18F-Galacto-RGD PET. 
Abstract:
The integrin alpha(v)beta(3) is a key player in angiogenesis and metastasis. Our aim was to study the uptake patterns of the alpha(v)beta(3)-selective PET tracer (18)F-galacto-RGD in invasive ductal breast cancer. METHODS: Sixteen patients with primary (n = 12) or metastasized breast cancer (n = 4) were examined with (18)F-galacto-RGD PET. Standardized uptake values (SUVs) were derived by region-of-interest analysis, and immunohistochemistry of alpha(v)beta(3) expression was performed (n = 5). R...    »
 
Zeitschriftentitel:
J Nucl Med 
Jahr:
2008 
Band / Volume:
49 
Heft / Issue:
Seitenangaben Beitrag:
255-9 
Sprache:
eng 
Print-ISSN:
0161-5505 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik; Frauenklinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie