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Document type:
journal article 
Author(s):
Knoeringer, M; Reinke, A; Trappe, AE; Schlegel, J 
Title:
Absence of the mutated Trp2 allele but a common polymorphism of the COL9A2 collagen gene is associated with early recurrence after lumbar discectomy in a German population. 
Abstract:
Genetic factors seem to play a role in symptomatic lumbar disc disease (LDD). It has been shown previously that a tryptophan mutation of the COL9A2 gene is a major risk factor for LDD in a Finish population. The impact of collagen gene variations on the relapse rate after lumbar discectomy, however, has not been studied so far. Here, we conducted a cross-sectional genotyping study of patients who underwent lumbar discectomy to determine the influence of a COL9A2 mutation on the recurrence rates....    »
 
Journal title abbreviation:
Eur Spine J 
Year:
2008 
Journal volume:
17 
Journal issue:
Pages contribution:
463-7 
Language:
eng 
Print-ISSN:
0940-6719 
TUM Institution:
Neurochirurgische Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie