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Dokumenttyp:
journal article 
Autor(en):
Schott, M; Sagert, C; Willenberg, HS; Schinner, S; Ramp, U; Varro, A; Raffel, A; Eisenberger, C; Zacharowski, K; Perren, A; Scherbaum, WA 
Titel:
Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger-Ellison's syndrome. 
Abstract:
CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the oxyntic mucosa. Gastrin and its derivates have been reported to regulate epithelial cell proliferation, migration, and differentiation. Mutations in the epithelial cadherin (E-cadherin) gene have been shown to be associated with the occurrence of diffuse gastric carcinomas in affected families. OBJECTIVE: In this study we investigated the histopathological and molecular...    »
 
Zeitschriftentitel:
J Clin Endocrinol Metab 
Jahr:
2007 
Band / Volume:
92 
Heft / Issue:
Seitenangaben Beitrag:
3378-82 
Sprache:
eng 
Print-ISSN:
0021-972X 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie