User: Guest  Login
Document type:
journal article 
Author(s):
Schott, M; Sagert, C; Willenberg, HS; Schinner, S; Ramp, U; Varro, A; Raffel, A; Eisenberger, C; Zacharowski, K; Perren, A; Scherbaum, WA 
Title:
Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger-Ellison's syndrome. 
Abstract:
CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the oxyntic mucosa. Gastrin and its derivates have been reported to regulate epithelial cell proliferation, migration, and differentiation. Mutations in the epithelial cadherin (E-cadherin) gene have been shown to be associated with the occurrence of diffuse gastric carcinomas in affected families. OBJECTIVE: In this study we investigated the histopathological and molecular...    »
 
Journal title abbreviation:
J Clin Endocrinol Metab 
Year:
2007 
Journal volume:
92 
Journal issue:
Pages contribution:
3378-82 
Language:
eng 
Print-ISSN:
0021-972X 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie