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Document type:
journal article 
Author(s):
Anlauf, M; Perren, A; Klöppel, G 
Title:
Endocrine precursor lesions and microadenomas of the duodenum and pancreas with and without MEN1: criteria, molecular concepts and clinical significance. 
Abstract:
Proliferative changes in the neuroendocrine cells that precede neoplasia are of interest for the understanding of tumorigenesis and the early recognition of neuroendocrine tumors. This review focuses on precursor lesions of duodenal and pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1 (MEN1) and also discusses 2 new disease entities of pancreatic microadenomatosis. The gastrinomas observed in MEN1 are almost exclusively localized in the duodenum and are multicentric. It ha...    »
 
Journal title abbreviation:
Pathobiology 
Year:
2007 
Journal volume:
74 
Journal issue:
Pages contribution:
279-84 
Language:
eng 
Print-ISSN:
1015-2008 
TUM Institution:
r Allgemeine Pathologie und pathologische Anatomie