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Dokumenttyp:
journal article 
Autor(en):
Lee, HJ; Lee, HS; Hur, K; Kim, WH; Yanagihara, K; Becker, KF; Lee, KU; Yang, HK 
Titel:
Tumor specificity and in vivo targeting of an antibody against exon 9 deleted E-cadherin in gastric cancer. 
Abstract:
PURPOSE: The aim of this study was to evaluate the possibility of using a monoclonal antibody against exon 9 deleted E-cadherin (E-cad delta 9-1) for immunotherapy of gastric cancer. METHODS: Among nine human diffuse-type gastric cancer cell lines, we selected a cell line expressing exon 9 deleted E-cadherin (HSC-45M2) by direct sequencing. Tumor specificity and tumor specific in vivo targeting of E-cad delta 9-1 were evaluated in nude mouse bearing a tumor derived from HSC-45M2 cell line by imm...    »
 
Zeitschriftentitel:
J Cancer Res Clin Oncol 
Jahr:
2007 
Band / Volume:
133 
Heft / Issue:
12 
Seitenangaben Beitrag:
987-94 
Sprache:
eng 
Print-ISSN:
0171-5216 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie