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Dokumenttyp:
journal article 
Autor(en):
Lehmann, R; Zuellig, RA; Kugelmeier, P; Baenninger, PB; Moritz, W; Perren, A; Clavien, PA; Weber, M; Spinas, GA 
Titel:
Superiority of small islets in human islet transplantation. 
Abstract:
Many factors influence the outcome of islet transplantation. As islets in the early posttransplant setting are supplied with oxygen by diffusion only and are in a hypoxic state in the portal system, we tested whether small human islets are superior to large islets both in vitro and in vivo. We assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, we analyzed the influenc...    »
 
Zeitschriftentitel:
Diabetes 
Jahr:
2007 
Band / Volume:
56 
Heft / Issue:
Seitenangaben Beitrag:
594-603 
Sprache:
eng 
Print-ISSN:
0012-1797 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie