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Document type:
journal article 
Author(s):
Becker, KF; Schott, C; Hipp, S; Metzger, V; Porschewski, P; Beck, R; Nährig, J; Becker, I; Höfler, H 
Title:
Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis. 
Abstract:
Owing to its cross-linking effects, it is currently believed that formalin fixation of routinely processed tissues in the clinic prevents protein extraction and profiling. The aim of our study was to develop a robust, fast, standardized, and easy to use technique for the solubilization of non-degraded, full length, and immunoreactive proteins from formalin-fixed tissues for western blot and protein microarray analysis. Sections of routinely processed formalin-fixed and paraffin-embedded tissues...    »
 
Journal title abbreviation:
J Pathol 
Year:
2007 
Journal volume:
211 
Journal issue:
Pages contribution:
370-8 
Language:
eng 
Print-ISSN:
0022-3417 
TUM Institution:
r Allgemeine Pathologie und pathologische Anatomie