User: Guest  Login
Document type:
journal article 
Author(s):
Eyer, F; Jung, N; Neuberger, H; Schulz, R; Steiner, K; Ladstetter, B; Poethko, T; Henke, J; Zilker, T 
Title:
Enteral exsorption of acetaminophen after intravenous injection in rats: influence of activated charcoal on this clearance path. 
Abstract:
The fate of acetaminophen after intravenous injection in whole bowel-irrigated rats (n = 40) and the influence of activated charcoal on the kinetics were investigated. After randomization to four groups (n = 10, each group), plasma concentration and the quantities of acetaminophen and metabolites excreted into bile, urine and intestine were determined using an in vivo model with or without orally administered activated charcoal and with or without bile duct cannulation. The cumulative amount of...    »
 
Journal title abbreviation:
Basic Clin Pharmacol Toxicol 
Year:
2007 
Journal volume:
101 
Journal issue:
Pages contribution:
163-71 
Language:
eng 
Print-ISSN:
1742-7835 
TUM Institution:
Toxikologische Abteilung; Nuklearmedizinische Klinik und Poliklinik