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Document type:
journal article 
Author(s):
Nieder, C; Schnaiter, A; Weber, WA; Schill, S; Andratschke, N; Schwaiger, M; Molls, M 
Title:
Detrimental effects of an antibody directed against tumor necrosis factor alpha in experimental kidney irradiation. 
Abstract:
Antibodies directed against tumor necrosis factor (TNF)-alpha are clinically used for Crohn's disease, rheumatoid arthritis and psoriasis. TNF-alpha is also an important cytokine in radiotherapy because it mediates inflammatory responses in normal tissues. To study the influence of TNF-alpha inhibition on radiation toxicity, we used a well-established mouse model of kidney irradiation, where the portal also includes parts of the intestine. Mice were treated with single-fraction radiotherapy to t...    »
 
Journal title abbreviation:
Anticancer Res 
Year:
2007 
Journal volume:
27 
Journal issue:
4B 
Pages contribution:
2353-7 
Language:
eng 
Print-ISSN:
0250-7005 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie ; Nuklearmedizinische Klinik und Poliklinik