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Document type:
journal article 
Author(s):
Nieder, C; Cai, L; Weber, WA; Schill, S; Andratschke, N; Schwaiger, M; Molls, M 
Title:
Evaluation of insulin-like growth factor-1 in a mouse model of long-term abdominal radiation toxicity. 
Abstract:
The purpose of these experiments was to test whether a brief course of insulin-like growth factor-1 (IGF-1) injection (escalating doses) concomitant to irradiation ameliorates radiation-induced kidney dysfunction and lethal bowel toxicity in a mouse model of unilateral high-dose irradiation of the kidney and adjacent bowel. The kidney function was assessed by means of repeated 99mTc-dimercaptosuccinate scans (every six weeks) during a maximum follow-up of 49 weeks. The experiments with single fr...    »
 
Journal title abbreviation:
Anticancer Res 
Year:
2007 
Journal volume:
27 
Journal issue:
1A 
Pages contribution:
183-7 
Language:
eng 
Print-ISSN:
0250-7005 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie ; Nuklearmedizinische Klinik und Poliklinik