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Document type:
journal article 
Author(s):
Garaschuk, O; Griesbeck, O; Konnerth, A 
Title:
Troponin C-based biosensors: a new family of genetically encoded indicators for in vivo calcium imaging in the nervous system. 
Abstract:
Fluorescence imaging represents a powerful approach for the detection of intracellular Ca(2+) signals in vivo. With appropriate techniques, Ca(2+) signals can be recorded at many levels of complexity, ranging from large scale neuronal networks down to individual presynaptic boutons or postsynaptic spines. Here we review the applicability of genetically encoded Ca(2+) indicators for in vivo Ca(2+) imaging of neural function. We describe some of the recent progress in sensor design and evaluate th...    »
 
Journal title abbreviation:
Cell Calcium 
Year:
2007 
Journal volume:
42 
Journal issue:
4-5 
Pages contribution:
351-61 
Language:
eng 
Print-ISSN:
0143-4160 
TUM Institution:
r Neurowissenschaften