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Dokumenttyp:
journal article 
Autor(en):
Quintana, FJ; Basso, AS; Iglesias, AH; Korn, T; Farez, MF; Bettelli, E; Caccamo, M; Oukka, M; Weiner, HL 
Titel:
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. 
Abstract:
Regulatory T cells (T(reg)) expressing the transcription factor Foxp3 control the autoreactive components of the immune system. The development of T(reg) cells is reciprocally related to that of pro-inflammatory T cells producing interleukin-17 (T(H)17). Although T(reg) cell dysfunction and/or T(H)17 cell dysregulation are thought to contribute to the development of autoimmune disorders, little is known about the physiological pathways that control the generation of these cell lineages. Here we...    »
 
Zeitschriftentitel:
Nature 
Jahr:
2008 
Band / Volume:
453 
Heft / Issue:
7191 
Seitenangaben Beitrag:
65-71 
Sprache:
eng 
Print-ISSN:
0028-0836 
TUM Einrichtung:
Neurologische Klinik und Poliklinik