CT-perfusion imaging of the human brain: advanced deconvolution analysis using circulant singular value decomposition.

Wittsack, HJ; Wohlschläger, AM; Ritzl, EK; Kleiser, R; Cohnen, M; Seitz, RJ; Mödder, U

doi:10.1016/j.compmedimag.2007.09.004

journal article

Dokumenttyp:: Journal Article; Article
Autor(en):: Wittsack, HJ; Wohlschläger, AM; Ritzl, EK; Kleiser, R; Cohnen, M; Seitz, RJ; Mödder, U
Titel:: CT-perfusion imaging of the human brain: advanced deconvolution analysis using circulant singular value decomposition.
Abstract:: According to indicator dilution theory tissue time-concentration curves have to be deconvolved with arterial input curves in order to get valid perfusion results. Our aim was to adapt and validate a deconvolution method originating from magnetic resonance techniques and apply it to the calculation of dynamic contrast enhanced computed tomography perfusion imaging. The application of a block-circulant matrix approach for singular value decomposition renders the analysis independent of tracer arrival time to improve the results. «
According to indicator dilution theory tissue time-concentration curves have to be deconvolved with arterial input curves in order to get valid perfusion results. Our aim was to adapt and validate a deconvolution method originating from magnetic resonance techniques and apply it to the calculation of dynamic contrast enhanced computed tomography perfusion imaging. The application of a block-circulant matrix approach for singular value decomposition renders the analysis independent of tracer arri... »
Zeitschriftentitel:: Comput Med Imaging Graph
Jahr:: 2008
Band / Volume:: 32
Heft / Issue:: 1
Seitenangaben Beitrag:: 67-77
Sprache:: eng
Volltext / DOI:: doi:10.1016/j.compmedimag.2007.09.004
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/18029143
Print-ISSN:: 0895-6111
TUM Einrichtung:: Fachgebiet Neuroradiologie (Prof. Zimmer); Neurologische Klinik und Poliklinik
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