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Document type:
journal article 
Author(s):
Valet, M; Pfab, F; Sprenger, T; Wöller, A; Zimmer, C; Behrendt, H; Ring, J; Darsow, U; Tölle, TR 
Title:
Cerebral processing of histamine-induced itch using short-term alternating temperature modulation--an FMRI study. 
Abstract:
Human neuroimaging studies on the physiology of itch have been hampered by the lack of reproducible "on-off" stimuli. Using a previously established biphasic temperature stimulus model, we investigated the cerebral activation pattern of itch processing in 12 healthy volunteers with functional magnetic resonance imaging. Itch was provoked on the right forearm with skin prick application of 1% histamine-dihydrochloride. Local temperature modulation allowed reproducible itch provocation above scrat...    »
 
Journal title abbreviation:
J Invest Dermatol 
Year:
2008 
Journal volume:
128 
Journal issue:
Pages contribution:
426-33 
Language:
eng 
Print-ISSN:
0022-202X 
TUM Institution:
Neurologische Klinik und Poliklinik; r Dermatologie und Allergologie; r Neuroradiologie