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Document type:
journal article 
Author(s):
Stüve, O; Marra, CM; Cravens, PD; Singh, MP; Hu, W; Lovett-Racke, A; Monson, NL; Phillips, JT; Cohen Tervaert, JW; Nash, RA; Hartung, HP; Kieseier, BC; Racke, MM; Frohman, EM; Hemmer, B 
Title:
Potential risk of progressive multifocal leukoencephalopathy with natalizumab therapy: possible interventions. 
Abstract:
Natalizumab (Tysabri) is an effective therapy for multiple sclerosis. Recently, 3 patients who were treated with natalizumab developed progressive multifocal leukoencephalopathy (PML), an opportunistic infection of the brain with the polyomavirus JC. The pathogenesis of natalizumab-associated PML may be different from that of PML not associated with the drug. We reviewed biologically feasible interventions for patients diagnosed as having PML or other infections while receiving natalizumab thera...    »
 
Journal title abbreviation:
Arch Neurol 
Year:
2007 
Journal volume:
64 
Journal issue:
Pages contribution:
169-76 
Language:
eng 
Print-ISSN:
0003-9942 
TUM Institution:
Neurologische Klinik und Poliklinik