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Dokumenttyp:
journal article 
Autor(en):
Hemmer, B; Hartung, HP 
Titel:
Toward the development of rational therapies in multiple sclerosis: what is on the horizon? 
Abstract:
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support an autoimmune pathogenesis on the background of a complex interaction between multiple genes and environmental factors. Accordingly, targeting the immune system has been a rational approach for the treatment of MS. The development of disease-modifying immunomodulatory drugs with partial efficacy, coupled with advances in understanding the pathophysiology and pathology of MS, has provided momentum to explore...    »
 
Zeitschriftentitel:
Ann Neurol 
Jahr:
2007 
Band / Volume:
62 
Heft / Issue:
Seitenangaben Beitrag:
314-26 
Sprache:
eng 
Print-ISSN:
0364-5134 
TUM Einrichtung:
Neurologische Klinik und Poliklinik