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Document type:
journal article 
Author(s):
Hemmer, B; Hartung, HP 
Title:
Toward the development of rational therapies in multiple sclerosis: what is on the horizon? 
Abstract:
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support an autoimmune pathogenesis on the background of a complex interaction between multiple genes and environmental factors. Accordingly, targeting the immune system has been a rational approach for the treatment of MS. The development of disease-modifying immunomodulatory drugs with partial efficacy, coupled with advances in understanding the pathophysiology and pathology of MS, has provided momentum to explore...    »
 
Journal title abbreviation:
Ann Neurol 
Year:
2007 
Journal volume:
62 
Journal issue:
Pages contribution:
314-26 
Language:
eng 
Print-ISSN:
0364-5134 
TUM Institution:
Neurologische Klinik und Poliklinik