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Document type:
journal article 
Author(s):
Michalke, B; Berthele, A; Mistriotis, P; Ochsenkühn-Petropoulou, M; Halbach, S 
Title:
Manganese species from human serum, cerebrospinal fluid analyzed by size exclusion chromatography-, capillary electrophoresis coupled to inductively coupled plasma mass spectrometry. 
Abstract:
Manganese (Mn) at high concentrations can have adverse effects on health, mainly because of its toxicity to the central nervous system. Health impacts of Mn are known mostly from occupational health studies, but the exact mechanisms how Mn, being bound to transferrin (TF) in the blood, enters the brain--are unknown. Mn speciation at the neural barriers can help to obtain more information about the pathways and carriers. This paper summarizes investigations on the size distribution of Mn carriers...    »
 
Journal title abbreviation:
J Trace Elem Med Biol 
Year:
2007 
Journal volume:
21 Suppl 1 
Pages contribution:
4-9 
Language:
eng 
Print-ISSN:
0946-672X 
TUM Institution:
Neurologische Klinik und Poliklinik