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Document type:
journal article 
Author(s):
Cepok, S; von Geldern, G; Nolting, T; Grummel, V; Srivastava, R; Zhou, D; Hartung, HP; Adams, O; Arendt, G; Hemmer, B 
Title:
Viral load determines the B-cell response in the cerebrospinal fluid during human immunodeficiency virus infection. 
Abstract:
OBJECTIVE: Human immunodeficiency virus (HIV) infection of the central nervous system (CNS) is frequently associated with intrathecal immunoglobulin synthesis and cerebrospinal fluid (CSF) pleocytosis, but little is known about the B-cell response in the CSF of these patients. In this study, we investigated the relation between virus load and the frequency and phenotype of B cells in the CSF of HIV-infected patients. METHODS: The distribution of T cells, B cells, short-lived plasmablasts, and lo...    »
 
Journal title abbreviation:
Ann Neurol 
Year:
2007 
Journal volume:
62 
Journal issue:
Pages contribution:
458-67 
Language:
eng 
Print-ISSN:
0364-5134 
TUM Institution:
Neurologische Klinik und Poliklinik