User: Guest  Login
Document type:
journal article 
Author(s):
Mühlau, M; Weindl, A; Wohlschläger, AM; Gaser, C; Städtler, M; Valet, M; Zimmer, C; Kassubek, J; Peinemann, A 
Title:
Voxel-based morphometry indicates relative preservation of the limbic prefrontal cortex in early Huntington disease. 
Abstract:
In Huntington disease (HD), both the genetic defect and mutant gene product huntington are known but the exact mechanisms that lead to neuronal loss are poorly understood. Until now, the distribution of tissue loss throughout the brain has been investigated intensively. Here we searched for areas that, antipodal to the striatum, display grey-matter (GM) preservation. We performed high resolution T1-weighted magnetic resonance imaging and voxel-based morphometry in 46 patients in early HD and 46...    »
 
Journal title abbreviation:
J Neural Transm 
Year:
2007 
Journal volume:
114 
Journal issue:
Pages contribution:
367-72 
Language:
eng 
Print-ISSN:
0300-9564 
TUM Institution:
Neurologische Klinik und Poliklinik; r Neuroradiologie