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Dokumenttyp:
journal article 
Autor(en):
Lutz, J; Huang, H; Deng, M; Wagner, B; Roos, M; Schmaderer, C; Strobl, M; Heemann, U 
Titel:
The effect of FK778 on the progression of chronic allograft nephropathy in a rat model. 
Abstract:
BACKGROUND: Chronic allograft nephropathy (CAN) still belongs to the leading causes of graft loss over the long term. The leflunomide derivative FK778 is a novel immunosuppressant with improved pharmacokinetic properties that effectively prolonged graft survival in several transplantation models. In the present study, we investigated the effects of FK778 at different phases after transplantation on the progression of CAN. METHODS: Fisher 344 kidneys were orthotopically transplanted into Lewis re...    »
 
Zeitschriftentitel:
Transplantation 
Jahr:
2007 
Band / Volume:
83 
Heft / Issue:
Seitenangaben Beitrag:
741-6 
Sprache:
eng 
Print-ISSN:
0041-1337 
TUM Einrichtung:
r Nephrologie