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Dokumenttyp:
journal article 
Autor(en):
Lutz, J; Lu, R; Strobl, M; Huang, H; Deng, M; Wang, M; Ouyang, N; Heemann, U 
Titel:
ICOS/B7RP-1 interference in mouse kidney transplantation. 
Abstract:
BACKGROUND: Activated T cells play a key role in allograft rejection. T cell activation requires signaling via the T cell receptor as well as costimulatory signals. Inducible costimulatory molecule (ICOS), with its ligand B7RP-1, is a recently discovered costimulatory molecule of the CD28 family. The role of this signaling pathway during the early phases of kidney allograft rejection is not clear so far. METHODS: Kidneys were orthotopically transplanted from BALB/c to C57BL/6 mice. Animals were...    »
 
Zeitschriftentitel:
Transplantation 
Jahr:
2007 
Band / Volume:
84 
Heft / Issue:
Seitenangaben Beitrag:
223-30 
Sprache:
eng 
Print-ISSN:
0041-1337 
TUM Einrichtung:
r Nephrologie