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Document type:
journal article 
Author(s):
Lutz, J; Lu, R; Strobl, M; Huang, H; Deng, M; Wang, M; Ouyang, N; Heemann, U 
Title:
ICOS/B7RP-1 interference in mouse kidney transplantation. 
Abstract:
BACKGROUND: Activated T cells play a key role in allograft rejection. T cell activation requires signaling via the T cell receptor as well as costimulatory signals. Inducible costimulatory molecule (ICOS), with its ligand B7RP-1, is a recently discovered costimulatory molecule of the CD28 family. The role of this signaling pathway during the early phases of kidney allograft rejection is not clear so far. METHODS: Kidneys were orthotopically transplanted from BALB/c to C57BL/6 mice. Animals were...    »
 
Journal title abbreviation:
Transplantation 
Year:
2007 
Journal volume:
84 
Journal issue:
Pages contribution:
223-30 
Language:
eng 
Print-ISSN:
0041-1337 
TUM Institution:
Abteilung für Nephrologie