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Dokumenttyp:
journal article 
Autor(en):
Rodríguez, N; Mages, J; Dietrich, H; Wantia, N; Wagner, H; Lang, R; Miethke, T 
Titel:
MyD88-dependent changes in the pulmonary transcriptome after infection with Chlamydia pneumoniae. 
Abstract:
Chlamydia pneumoniae, an intracellular bacterium, causes pneumonia in humans and mice. Toll-like receptors and the key adaptor molecule myeloid differentiation factor-88 (MyD88) play a critical role in inducing immunity against this microorganism and are crucial for survival. To explore the influence of MyD88 on induction of immune responses in vivo on a genome-wide level, wildtype (WT) or MyD88(-/-) mice were infected with C. pneumoniae on anesthesia, and the pulmonary transcriptome was analyze...    »
 
Zeitschriftentitel:
Physiol Genomics 
Jahr:
2007 
Band / Volume:
30 
Heft / Issue:
Seitenangaben Beitrag:
134-45 
Sprache:
eng 
Print-ISSN:
1094-8341 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene