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Dokumenttyp:
journal article 
Autor(en):
Autenrieth, SE; Soldanova, I; Rösemann, R; Gunst, D; Zahir, N; Kracht, M; Ruckdeschel, K; Wagner, H; Borgmann, S; Autenrieth, IB 
Titel:
Yersinia enterocolitica YopP inhibits MAP kinase-mediated antigen uptake in dendritic cells. 
Abstract:
Yersinia enterocolitica (Ye) targets mouse dendritic cells (DCs) and inhibits their ability to trigger T cell activation. Here we have investigated whether Ye might interfere with antigen presentation in DCs. Infection of DCs with the Ye wild-type strain reduced OVA uptake by DCs as demonstrated by flow cytometry and confocal laser scan microscopy. In contrast, DCs infected with Yersinia outer protein P (YopP)-deficient mutant strain rapidly internalized OVA. Furthermore, transfection of DCs wit...    »
 
Zeitschriftentitel:
Cell Microbiol 
Jahr:
2007 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
425-37 
Sprache:
eng 
Print-ISSN:
1462-5814 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene