User: Guest  Login
Document type:
journal article 
Author(s):
Cappello, C; Saugel, B; Huth, KC; Zwergal, A; Krautkrämer, M; Furman, C; Rouis, M; Wieser, B; Schneider, HW; Neumeier, D; Brand, K 
Title:
Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling. 
Abstract:
OBJECTIVE: Recent studies have provided strong evidence for the presence of ozone in atherosclerotic lesions. In addition, modification of LDL has been suggested to be involved in atherosclerosis. In the present study we wanted to investigate whether LDL exposed to ozone (ozLDL) is able to modulate the NF-kappaB system, as a paradigm for inflammatory signaling. METHODS AND RESULTS: We showed that activation of NF-kappaB by lipopolysaccharide (LPS), a prototypic inducer of innate immunity, was re...    »
 
Journal title abbreviation:
Arterioscler Thromb Vasc Biol 
Year:
2007 
Journal volume:
27 
Journal issue:
Pages contribution:
226-32 
Language:
eng 
Print-ISSN:
1079-5642 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie