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Dokumenttyp:
journal article 
Autor(en):
Cappello, C; Saugel, B; Huth, KC; Zwergal, A; Krautkrämer, M; Furman, C; Rouis, M; Wieser, B; Schneider, HW; Neumeier, D; Brand, K 
Titel:
Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling. 
Abstract:
OBJECTIVE: Recent studies have provided strong evidence for the presence of ozone in atherosclerotic lesions. In addition, modification of LDL has been suggested to be involved in atherosclerosis. In the present study we wanted to investigate whether LDL exposed to ozone (ozLDL) is able to modulate the NF-kappaB system, as a paradigm for inflammatory signaling. METHODS AND RESULTS: We showed that activation of NF-kappaB by lipopolysaccharide (LPS), a prototypic inducer of innate immunity, was re...    »
 
Zeitschriftentitel:
Arterioscler Thromb Vasc Biol 
Jahr:
2007 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
226-32 
Sprache:
eng 
Print-ISSN:
1079-5642 
TUM Einrichtung:
r Klinische Chemie und Pathobiochemie