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Document type:
journal article 
Author(s):
Adhikary, D; Behrends, U; Boerschmann, H; Pfünder, A; Burdach, S; Moosmann, A; Witter, K; Bornkamm, GW; Mautner, J 
Title:
Immunodominance of lytic cycle antigens in epstein-barr virus-specific CD4+ T cell preparations for therapy. 
Abstract:
BACKGROUND: Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer of polyclonal EBV-specific T cell lines containing CD4+ and CD8+ T cell components. Although patients receiving T cell preparations with a higher CD4+ T cell proportion show better clinical responses, the specificity of the infused CD4...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2007 
Journal volume:
Journal issue:
Pages contribution:
e583 
Language:
eng 
TUM Institution:
Kinderklinik und Poliklinik