Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Bonello, S; Zähringer, C; BelAiba, RS; Djordjevic, T; Hess, J; Michiels, C; Kietzmann, T; Görlach, A 
Titel:
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site. 
Abstract:
OBJECTIVE: Reactive oxygen species have been implicated as signaling molecules modulating the activity of redox-sensitive transcription factors such as nuclear factor kappa B (NF-kappaB). Recently, the transcription factor hypoxia-inducible factor-1 (HIF-1), known to mediate gene expression by hypoxia, has been found to be also activated by nonhypoxic factors in a redox-sensitive manner. We therefore aimed to elucidate the link between these 2 important redox-sensitive transcription factors. MET...    »
 
Zeitschriftentitel:
Arterioscler Thromb Vasc Biol 
Jahr:
2007 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
755-61 
Sprache:
eng 
Print-ISSN:
1079-5642 
TUM Einrichtung:
r Kinderkardiologie und angeborene Herzfehler