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Dokumenttyp:
journal article 
Autor(en):
Gamboa-Dominguez, A; Seidl, S; Reyes-Gutierrez, E; Hermannstädter, C; Quintanilla-Martinez, L; Busch, R; Höfler, H; Fend, F; Luber, B 
Titel:
Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer. 
Abstract:
BACKGROUND: Gastric carcinoma is characterised by numerous genetic and epigenetic alterations that influence cell cycle progression, apoptosis and DNA repair. These alterations include down-regulation of the cyclin-dependent kinase (CDK) inhibitors p21(WAF1/CIP1) and p27(Kip1), and mutations of the tumour suppressor protein p53 and the cell adhesion molecule E-cadherin. Combined evaluation of the prognostic significance of these alterations has not been reported in Mexican Mestizo patients. AIMS...    »
 
Zeitschriftentitel:
J Clin Pathol 
Jahr:
2007 
Band / Volume:
60 
Heft / Issue:
Seitenangaben Beitrag:
756-61 
Sprache:
eng 
Print-ISSN:
0021-9746 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; r Medizinische Statistik und Epidemiologie