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Dokumenttyp:
journal article 
Autor(en):
Kaltz, N; Funari, A; Hippauf, S; Delorme, B; Noël, D; Rimminucci, M; Jacobs, VR; Häupl, T; Jorgensen, C; Charbord, P; Peschel, C; Bianco, P; Oostendorp, RA 
Titel:
In vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes. 
Abstract:
Expression of "stemness" markers is widely used as a predictor of stem cell properties of mesenchymal stem cells (MSC). Here, we show that bone marrow-derived (BM)-MSC show stem cell-like behavior in vivo; that is, they form ossicles with formation of bone, formation of adipocytes, and establishment of the murine hematopoietic microenvironment. Multipotent umbilical vein-derived stromal cells (UVSC), on the other hand, do not form bone, nor do they give rise to adipocytes in vivo. Despite these...    »
 
Zeitschriftentitel:
Stem Cells 
Jahr:
2008 
Band / Volume:
26 
Heft / Issue:
Seitenangaben Beitrag:
2419-24 
Sprache:
eng 
Print-ISSN:
1066-5099 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik; Frauenklinik und Poliklinik