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Dokumenttyp:
journal article 
Autor(en):
Meier, R; Piert, M; Piontek, G; Rudelius, M; Oostendorp, RA; Senekowitsch-Schmidtke, R; Henning, TD; Wels, WS; Uherek, C; Rummeny, EJ; Daldrup-Link, HE 
Titel:
Tracking of [(18)F]FDG-labeled natural killer cells to HER2/neu-positive tumors. 
Abstract:
INTRODUCTION: The objective of this study was to label the human natural killer (NK) cell line NK-92 with [(18)F]fluoro-deoxy-glucose (FDG) for subsequent in vivo tracking to HER2/neu-positive tumors. METHODS: NK-92 cells were genetically modified to NK-92-scFv(FRP5)-zeta cells, which express a chimeric antigen receptor that is specific to the tumor-associated ErbB2 (HER2/neu) antigen. NK-92 and NK-92-scFv(FRP5)-zeta cells were labeled with [(18)F]FDG by simple incubation at different settings....    »
 
Zeitschriftentitel:
Nucl Med Biol 
Jahr:
2008 
Band / Volume:
35 
Heft / Issue:
Seitenangaben Beitrag:
579-88 
Sprache:
eng 
Print-ISSN:
0969-8051 
TUM Einrichtung:
r Radiologie; r Allgemeine Pathologie und pathologische Anatomie; III. Medizinische Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik