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Document type:
journal article 
Author(s):
Beer, AJ; Holzapfel, K; Neudorfer, J; Piontek, G; Settles, M; Krönig, H; Peschel, C; Schlegel, J; Rummeny, EJ; Bernhard, H 
Title:
Visualization of antigen-specific human cytotoxic T lymphocytes labeled with superparamagnetic iron-oxide particles. 
Abstract:
New technologies are needed to characterize the migration and survival of antigen-specific T cells in vivo. In this study, we developed a novel technique for the labeling of human cytotoxic T lymphocytes with superparamagnetic iron-oxide particles and the subsequent depiction with a conventional 1.5-T magnetic resonance scanner. Antigen-specific CD8(+) T lymphocytes were labeled with ferucarbotran by lipofection. The uptake of ferucarbotran was confirmed by immunofluorescence microscopy using a...    »
 
Journal title abbreviation:
Eur Radiol 
Year:
2008 
Journal volume:
18 
Journal issue:
Pages contribution:
1087-95 
Language:
eng 
Print-ISSN:
0938-7994 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik; r Radiologie; III. Medizinische Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie