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Dokumenttyp:
journal article 
Autor(en):
Burmeister, T; Schwartz, S; Taubald, A; Jost, E; Lipp, T; Schneller, F; Diedrich, H; Thomssen, H; Mey, UJ; Eucker, J; Rieder, H; Gökbuget, N; Hoelzer, D; Thiel, E 
Titel:
Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. 
Abstract:
RT-PCR detects chimeric BCR-ABL mRNA in approximately 25% of adult acute lymphoblastic leukemia (ALL) cases. Minor breakpoint transcripts (e1a2) are found in about 70% of positive cases and major breakpoint transcripts (e13a2, e14a2) in about 30% of cases. However, other atypical transcripts are sometimes observed. We report experience gained in the GMALL Study Group and identified 8 BCR-ABL-positive adult ALL cases with such atypical transcripts: 5 with e1a3, 2 with e13a3 (b2a3), and 1 with e6a...    »
 
Zeitschriftentitel:
Haematologica 
Jahr:
2007 
Band / Volume:
92 
Heft / Issue:
12 
Seitenangaben Beitrag:
1699-702 
Sprache:
eng 
Print-ISSN:
0390-6078 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik