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Document type:
journal article 
Author(s):
Boeck, S; Weigang-Köhler, K; Fuchs, M; Kettner, E; Quietzsch, D; Trojan, J; Stötzer, O; Zeuzem, S; Lordick, F; Köhne, CH; Kröning, H; Steinmetz, T; Depenbrock, H; Heinemann, V 
Title:
Second-line chemotherapy with pemetrexed after gemcitabine failure in patients with advanced pancreatic cancer: a multicenter phase II trial. 
Abstract:
BACKGROUND: A standard second-line chemotherapy regimen has yet to be defined for patients with gemcitabine (Gem)-refractory advanced pancreatic cancer (PC). PATIENTS AND METHODS: In this multicenter phase II trial, patients with unresectable or metastatic PC who had progressed on single-agent Gem or a Gem-containing regimen received pemetrexed 500 mg/m(2) as a 10-min infusion every 3 weeks until disease progression or occurrence of unacceptable toxicity. The primary end point was the 3-month su...    »
 
Journal title abbreviation:
Ann Oncol 
Year:
2007 
Journal volume:
18 
Journal issue:
Pages contribution:
745-51 
Language:
eng 
Print-ISSN:
0923-7534 
TUM Institution:
III. Medizinische Klinik und Poliklinik