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Document type:
journal article 
Author(s):
Eisenächer, K; Steinberg, C; Reindl, W; Krug, A 
Title:
The role of viral nucleic acid recognition in dendritic cells for innate and adaptive antiviral immunity. 
Abstract:
Dendritic cells which are located at the interface of innate and adaptive immunity are targets for infection by many different DNA and RNA viruses. Dendritic cell subpopulations express specific nucleic acid recognition receptors belonging to the Toll-like receptor family (TLR3, 7, 8, 9) and the cytosolic RNA helicase family (RIG-I, MDA5, LGP2). Activation of dendritic cells by viral DNA and RNA via these receptors is essential for triggering the innate antiviral immune response and shaping the...    »
 
Journal title abbreviation:
Immunobiology 
Year:
2007 
Journal volume:
212 
Journal issue:
9-10 
Pages contribution:
701-14 
Language:
eng 
Print-ISSN:
0171-2985 
TUM Institution:
II. Medizinische Klinik und Poliklinik