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Document type:
journal article 
Author(s):
Aichler, M; Algül, H; Behne, D; Hölzlwimmer, G; Michalke, B; Quintanilla-Martinez, L; Schmidt, J; Schmid, RM; Brielmeier, M 
Title:
Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF-alpha p53+/ mice. 
Abstract:
Genetic predisposition and environmental factors act in concert in the pathogenesis of multi-factorial diseases. Selenoproteins represent fundamental antioxidative systems for the maintenance of cellular redox homeostasis, which is altered in various disease processes. Optimal function of selenoproteins requires availability of sufficient amounts of the essential trace element selenium, but in many countries the nutritive selenium supply is regarded insufficient. Supplemental selenium has been s...    »
 
Journal title abbreviation:
Carcinogenesis 
Year:
2007 
Journal volume:
28 
Journal issue:
Pages contribution:
2002-7 
Language:
eng 
Print-ISSN:
0143-3334 
TUM Institution:
II. Medizinische Klinik und Poliklinik