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Document type:
journal article 
Author(s):
Moretti, A; Lam, J; Evans, SM; Laugwitz, KL 
Title:
Biology of Isl1+ cardiac progenitor cells in development and disease. 
Abstract:
The LIM-homeodomain transcription factor Islet-1 (Isl1) marks a cell population which makes a substantial contribution to the embryonic heart. Isl1 expression is downregulated as soon as the cells adopt a differentiated phenotype, suggesting that this transcription factor delineates a cardiogenic progenitor cell population. Taking advantage of this developmental lineage marker, we have identified in the postnatal heart a novel cardiac cell type, which is capable of self-renewal and readily diffe...    »
 
Journal title abbreviation:
Cell Mol Life Sci 
Year:
2007 
Journal volume:
64 
Journal issue:
Pages contribution:
674-82 
Language:
eng 
Print-ISSN:
1420-682X 
TUM Institution:
I. Medizinische Klinik und Poliklinik