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Document type:
journal article 
Author(s):
Schulz, C; Schäfer, A; Stolla, M; Kerstan, S; Lorenz, M; von Brühl, ML; Schiemann, M; Bauersachs, J; Gloe, T; Busch, DH; Gawaz, M; Massberg, S 
Title:
Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets. 
Abstract:
BACKGROUND: The membrane-bound chemokine fractalkine (CX3CL1) is expressed on various cell types such as activated endothelial cells and has been implicated in the inflammatory process of atherosclerosis. The aim of the present study was to dissect the role of fractalkine in leukocyte recruitment to inflamed endothelium under arterial shear forces. METHODS AND RESULTS: With the use of immunofluorescence and laminar flow assays, the present study shows that human umbilical vein endothelial cells...    »
 
Journal title abbreviation:
Circulation 
Year:
2007 
Journal volume:
116 
Journal issue:
Pages contribution:
764-73 
Language:
eng 
Print-ISSN:
0009-7322 
TUM Institution:
I. Medizinische Klinik und Poliklinik; r Medizinische Mikrobiologie, Immunologie und Hygiene