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Dokumenttyp:
journal article 
Autor(en):
Gaedtke, L; Pelisek, J; Lipinski, KS; Wrighton, CJ; Wagner, E 
Titel:
Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells. 
Abstract:
Nonviral transfections of six low passage human colon cancer cell lines using the artificial beta-catenin/TCF-dependent promoter CTP4 demonstrated a high promoter activity which was 1000- to 70000-fold higher than in HeLa control cells. Luciferase gene expression levels obtained with CTP4 in epithelial-like tumor cell cultures were only slightly lower than with the strong viral CMV promoter/enhancer, whereas in less differentiated tumor cultures CTP4 expression levels exceeded the CMV expression...    »
 
Zeitschriftentitel:
Mol Pharm 
Jahr:
2007 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
129-39 
Sprache:
eng 
Print-ISSN:
1543-8384 
TUM Einrichtung:
chirurgie