User: Guest  Login
Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Gaedtke, L; Pelisek, J; Lipinski, KS; Wrighton, CJ; Wagner, E 
Title:
Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells. 
Abstract:
Nonviral transfections of six low passage human colon cancer cell lines using the artificial beta-catenin/TCF-dependent promoter CTP4 demonstrated a high promoter activity which was 1000- to 70000-fold higher than in HeLa control cells. Luciferase gene expression levels obtained with CTP4 in epithelial-like tumor cell cultures were only slightly lower than with the strong viral CMV promoter/enhancer, whereas in less differentiated tumor cultures CTP4 expression levels exceeded the CMV expression...    »
 
Journal title abbreviation:
Mol Pharm 
Year:
2007 
Journal volume:
Journal issue:
Pages contribution:
129-39 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1543-8384 
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)