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Document type:
journal article 
Author(s):
Paepke, S; Jacobs, VR; Ohlinger, R; Warm, M; Kümmel, S; Thomas, A; Harbeck, N; Kiechle-Bahat, M 
Title:
Treatment strategies that effectively reduce early recurrence risk in postmenopausal women with endocrine-sensitive breast cancer: AIs upfront vs. switching. 
Abstract:
Several large, well-controlled clinical trials have now established that the aromatase inhibitors (AIs), including letrozole, anastrozole, and exemestane, are more effective than tamoxifen when used as adjuvant endocrine therapy in postmenopausal women with breast cancer. Yet, it is an open question as to how these drugs should be best integrated into the adjuvant treatment regimen. Both letrozole and anastrozole have shown efficacy over tamoxifen when used as initial adjuvant therapy (initiated...    »
 
Journal title abbreviation:
J Cancer Res Clin Oncol 
Year:
2007 
Journal volume:
133 
Journal issue:
12 
Pages contribution:
905-16 
Language:
eng 
Print-ISSN:
0171-5216 
TUM Institution:
Frauenklinik und Poliklinik