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Dokumenttyp:
journal article 
Autor(en):
Gross, E; Hölzl, G; Arnold, N; Hauenstein, E; Jacobsen, A; Schulze, K; Ramser, J; Meindl, A; Kiechle, M; Oefner, PJ 
Titel:
Allelic loss analysis by denaturing high-performance liquid chromatography and electrospray ionization mass spectrometry. 
Abstract:
Analysis of allelic imbalance is of great importance for understanding tumorigenesis and the clinical management of malignant disease. Fluorescent-based capillary electrophoresis (CE) of highly polymorphic short tandem repeats (STRs) has become the main method used to detect the loss/gain of alleles. However, there is continued interest in the development of techniques that require no fluorescence and allow the rapid analysis of individual samples. One promising alternative is ion-pair reversed-...    »
 
Zeitschriftentitel:
Hum Mutat 
Jahr:
2007 
Band / Volume:
28 
Heft / Issue:
Seitenangaben Beitrag:
303-11 
Sprache:
eng 
Print-ISSN:
1059-7794 
TUM Einrichtung:
Frauenklinik und Poliklinik