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Dokumenttyp:
journal article 
Autor(en):
Dorn, J; Schmitt, M; Kates, R; Schmalfeldt, B; Kiechle, M; Scorilas, A; Diamandis, EP; Harbeck, N 
Titel:
Primary tumor levels of human tissue kallikreins affect surgical success and survival in ovarian cancer patients. 
Abstract:
PURPOSE: Proteolytic factors of the human tissue kallikrein (hK) family and the plasminogen activation system play a key role in tumor progression in various malignancies. We determined antigen levels of urokinase-type plasminogen activator (uPA), its inhibitor PAI-1, and hK5-8, hK10, hK11, and hK13 by ELISA in primary tumor tissue extracts of 142 International Federation of Gynecology and Obstetrics (FIGO) I to IV ovarian cancer patients (median follow-up 41 months). RESULTS: After radical surg...    »
 
Zeitschriftentitel:
Clin Cancer Res 
Jahr:
2007 
Band / Volume:
13 
Heft / Issue:
Seitenangaben Beitrag:
1742-8 
Sprache:
eng 
Print-ISSN:
1078-0432 
TUM Einrichtung:
Frauenklinik und Poliklinik